BeiGene earmarks $74M to build fourth facility in China
BeiGene is building a fourth facility in China with a budget of $74 million for the land and construction. According to its first-quarter earnings in an SEC filing on Wednesday, BeiGene acquired a...
View ArticleSenate appropriators question FDA commissioner on H5N1 virus prep
FDA Commissioner Rob Califf told the Senate Appropriations Committee on Wednesday that milk products are safe from the H5N1 bird flu virus that’s circulating, and the FDA is working with mRNA vaccine...
View ArticleTeva to close additional manufacturing sites as it enters next phase of...
Teva is getting ready to close the first chapter of its “pivot to growth” strategy. The company’s restructuring has involved manufacturing site closures, a shift away from some lower-margin generics,...
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Inside CVS Caremark’s move that broke Humira’s hold on the market
(This story is from our new Health Tech newsletter. If you’d like to sign up, just click here.) For the first time in April, biosimilars started to gain a larger share of the Humira market. Up until...
View ArticleAfter eight years with Sanofi, Frank Nestle departs as CSO, global head of...
Sanofi’s CSO and global head of research Frank Nestle is leaving the company, a representative confirmed to Endpoints News Wednesday. Nestle first took over both positions in 2020, promoted from his...
View ArticleHouse panel marks up bill to require PBMs to use a flat fee in Medicare
The House Ways and Means committee on Wednesday marked up legislation that would require pharmacy benefit managers to de-link their compensation from the price of a drug, adding to the bipartisan...
View ArticleLawmakers consider limiting how long existing WuXi contracts can continue
House members want drugmakers to end their existing contracts with WuXi AppTec and other Chinese firms by 2032, two sources told Endpoints News. The Biosecure Act, under its current Senate iteration,...
View ArticleCommit Biologics nabs Novo Holdings support in €16M seed round for complement...
Novo Holdings is pitching in to Commit Biologics’ seed funding for its research on “supercharging” antibodies to turn on the complement system, an approach that could potentially lead to treatments for...
View ArticleAardvark raises $85M to target hunger, not appetite, as it contemplates IPO,...
A small San Diego biotech wants to take a different approach to the weight loss drug R&D field by going after hunger rather than suppressing appetite like the wildly popular GLP-1 class. “Most...
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Novo Nordisk sees more to GLP-1's future in $600M pact with Flagship's Metaphore
Novo Nordisk is pairing up with another Flagship-founded biotech to create new obesity medications, and GLP-1 remains in the frame. The Danish pharma giant, which leads the GLP-1 field alongside Eli...
View ArticleAttovia reels in $105M from crossover investors to run multiple trials of I&I...
California biotech Attovia Therapeutics is back with a $105 million Series B just 11 months after unveiling with $60 million. The Fremont-based startup eyes a series of clinical trials in the crowded...
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CytomX’s Amgen-partnered T cell engager yields mixed Phase 1 data
CytomX and Amgen’s T cell engager showed mixed efficacy signals in an early trial in advanced solid tumors, sending the biotech’s shares down 37% even as analysts defended the data. The Phase 1a...
View ArticleTakeda to revamp in multiyear quest, pivots CAR-NK therapy from cancer to...
Takeda is launching a broad, multiyear restructuring, CEO Christophe Weber announced on Thursday. The company also said it is shifting its Phase 2 CAR-NK therapy from oncology to autoimmune diseases....
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Infectious disease biotech Bluejay raises $182M for hepatitis trials
California biotech Bluejay Therapeutics has secured a megaround to continue developing its treatment candidates for chronic hepatitis D and B. The $182 million Series C, disclosed Thursday morning,...
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Freeline unveils early efficacy signal for Gaucher gene therapy: #ASGCT24
BALTIMORE — Four patients with Gaucher disease were able to stop their regular treatments after receiving a one-time infusion of a gene therapy developed by Freeline Therapeutics. The four patients...
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Acelyrin's founding CEO steps down, company scraps earnings call
Shao-Lee Lin is stepping down as founding CEO of Acelyrin, a California drug developer that raised the largest biotech IPO in 2023 and subsequently ran into clinical hurdles with its lead immunology...
View ArticleRoyalty Pharma inks MS deal with ImmuNext; X4 sells its priority review voucher
Plus, news about Pacira Biosciences, Cassava Sciences, Merck, Monopar Therapeutics, Eli Lilly and Optinose: Royalty Pharma signs MS deal: The company will pay about $525 million in cash to buy the...
View ArticleInnovent says next-gen GLP-1 drug from Eli Lilly beats top diabetes med in...
A next-generation GLP-1 candidate from Eli Lilly has outdone an older Lilly drug in a Phase 3 trial involving Chinese patients with diabetes, Lilly partner Innovent announced late Wednesday. The...
View ArticleRapt Therapeutics winds down Phase 2 studies of lead candidate in wake of...
Rapt Therapeutics said it will close and unblind two mid-stage trials in atopic dermatitis and asthma after they were put on clinical hold earlier this year due to a case of liver failure. The company...
View ArticleNucleus RadioPharma makes Artbio’s radiopharma assets; Minaris manufactures...
Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. CDMO Nucleus RadioPharma is partnering with clinical-stage company...
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