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#WCLC25: AstraZeneca’s Tagrisso combo extends survival by 10 months in...

The combination of AstraZeneca’s Tagrisso and chemotherapy cut the risk of death by 23% compared to Tagrisso alone for patients with advanced EGFR-mutant lung cancer. In the FLAURA2 study's key overall...

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Rapport reveals promising open-label study data for epilepsy pill, heads to...

Rapport Therapeutics' shares {$RAPP} jumped 170% at market open Monday after it posted topline mid-stage data indicating that its epilepsy pill can cut seizure frequency. However, the trial was small...

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Biotech vet Harvey Berger steps into CEO role at Arena BioWorks

Less than two years after making their public debut, the founders of Arena BioWorks have tapped longtime biotech pro Harvey Berger to take over as CEO. And he’s just completed his first task by...

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BridgeBio's Phase 2 hypoparathyroidism data; FDA clears second pig kidney trial

Plus, news about Saol Therapeutics, Eisai, Takeda's Vonvendi, Junshi Biosciences, Belite Bio, Integra Therapeutics, Novonesis and Novo Nordisk: 📊 BridgeBio’s positive hypoparathyroidism results: The...

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Exclusive: Cancer care startup Daymark Health raises $20M

Cancer care startup Daymark Health has raised $20 million in Series A funding less than half a year after its seed raise, Endpoints News learned exclusively. That's according to a securities filing...

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LB Pharma seeks $228M in proposed IPO with hopes to be industry's first since...

LB Pharmaceuticals, a biotech developing a twist on the decades-old schizophrenia treatment amisulpride, estimates it could gain net proceeds of $228 million from a Nasdaq IPO. The New York-based...

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#WCLC25: BioNTech, Bristol Myers tout PD-L1xVEGF results in small cell lung...

BioNTech and Bristol Myers Squibb said their PD-L1xVEGF drug used alongside chemotherapy showed promise in a mid-stage study for an aggressive form of lung cancer. In the Phase 2 trial, the companies...

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Dianthus’ selective complement inhibitor yields Phase 2 success in myasthenia...

Dianthus Therapeutics on Monday shared positive mid-stage data in generalized myasthenia gravis for an antibody candidate that it believes has “pipeline-in-a-product” potential for neuromuscular...

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Eli Lilly’s Jaypirca shows ‘striking’ results in first-line lymphoma patients 

Eli Lilly’s Jaypirca met the primary endpoint in a Phase 3 blood cancer trial, bringing the BTK inhibitor one step closer to a potential approval for previously untreated patients with a type of...

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Pfizer reports new Covid-19 vaccine data from open-label study

Pfizer says a new formulation of its Covid-19 vaccine boosted antibody levels by at least four-fold in adults ahead of the upcoming respiratory season. The biopharma and Comirnaty co-developer BioNTech...

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New FDA approval pathway for n-of-1 therapies coming soon, Prasad says

The success story of baby KJ’s customized CRISPR therapy and the prospects for others like it have the FDA readying a new approval pathway for those with extremely limited treatment options. ...

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Summit plays defense for the first time as questions loom over Phase 3 data

Did Summit Therapeutics set expectations too high? Excitement has been building over its cancer drug ivonescimab over the last two years as the company, investors and clinicians all wondered if it...

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Ridge Bio raises $25M to help drugmakers come up with better ADCs

A new California startup announced itself Tuesday with $25 million in seed funding, some major scientific backers, and the hope of helping biopharma companies make better antibody-drug conjugates and...

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Novartis to spend $1.4B on Tourmaline Bio, gaining new heart drug

Novartis said Tuesday that it would buy Tourmaline Bio for $1.4 billion in a bid to revitalize its cardiovascular offering. The Swiss pharma said it would pay $48 per share in ...

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Eli Lilly offers AI models to biotechs with TuneLab launch

Eli Lilly is offering an unusual deal to any biotech: contribute some data, and in exchange, get access to many of Lilly's own AI models. The initiative, called TuneLab, debuted Tuesday with a dozen...

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Regeneron’s promising antibody for cat, birch allergies; Ascletis targets...

Plus, news about Anavex, Alnylam, Rapport Therapeutics, Dianthus Therapeutics, Ultragenyx, Atom Therapeutics, Alchemab, BioMarin, Amgen, Kyowa Kirin and Bristol Myers Squibb: 🤧 Regeneron’s allergy...

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Ideaya touts trio of cancer drugs as it eyes spot in precision oncology market

Ideaya Biosciences reiterated its goal of becoming a “global leader” in precision oncology over the next decade as it shared data from three early- to mid-stage cancer trials. Since its inception a...

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Trump may exempt some pharma products from tariffs in future trade deals

President Donald Trump is looking to strike more deals with trade partners and says he “may be willing” to exempt some pharmaceutical products from future tariffs. An executive order released last week...

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Regeneron and Sandoz patent deal clears path for Eylea biosimilar in 2026

Sandoz can sell its biosimilar version of Regeneron’s Eylea in the US by the end of 2026, following a patent settlement between the two companies. The generic drugmaker announced Tuesday that ...

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Samsung Bio secures $1.3B contract with ‘large-sized’ US pharma customer 

Samsung Biologics has pulled in another billion dollar contract, this time with an unnamed “large-sized” US pharma company. The $1.3 billion contract started on Aug. 29 and will run until the end of...

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Eric Green, who the Trump administration ousted from NIH, urges optimism

SAN DIEGO -- Thirty minutes into a speech extolling the achievements of genomic medicine, Eric Green addressed what he called the “elephant in the room": his forced departure as an NIH director. For 16...

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HHS outlines vaccine, drug strategy in new MAHA report

HHS on Tuesday unveiled its long-awaited Make America Healthy Again strategy report, including plans for changes to the childhood vaccine schedule, stricter oversight of how drugs are advertised to...

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Lundbeck to transfer commercial drugs to three partners in 27 markets

Lundbeck will partner out its commercial medicines in 27 markets by the end of this year, the brain health drugmaker said Tuesday. The Danish biopharma is handing off ...

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Endpoints livestream: Will the XBI ever go up again? 

Let’s talk about market structure! Now, before you yawn and click away, let me argue that this is one of the most important factors in how biotech stocks trade. How stocks get on the S ...

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