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Otsuka's Taiho buys Swiss startup Araris with three ADCs nearing the clinic

A small Swiss drug developer is being scooped up for its pipeline of three antibody-drug conjugates that offer a next-generation approach to the area of oncology R&D that has ballooned in recent...

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Curevo gets $110M for a shot against Shingrix, gets Moncef Slaoui and Tal...

A Seattle biotech trying to take on one of the world’s biggest vaccines has nabbed a megaround. It also named former Operation Warp Speed chief scientific advisor Moncef Slaoui as its board chair and...

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GRO Biosciences, working on recoded organisms, cuts most staff

GRO Biosciences, a small but ambitious biotech startup attempting to create novel protein drugs from genetically modified bacteria, has cut most of its staff after “efficacy issues” delayed its...

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Kennedy's anti-vaccine actions shouldn't surprise anyone

At the end of Robert F. Kennedy Jr.'s confirmation hearing, Senate HELP Committee Chairman Bill Cassidy (R-LA) raised a rhetorical question at the heart of whether Kennedy was the moderate he’d...

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Vertanical’s Phase 3 win for non-opioid painkiller; Apriori lays off 40% of...

Plus, news about Pillar, vTv Therapeutics, OPKO Health, Entera Bio, Zentalis, Sutro Biopharma and Idorsia: Vertanical’s non-opioid painkiller succeeds in Phase 3: The German biotech claimed a...

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Orca Bio's T cell therapy may help blood cancer patients avoid transplant issues

Orca Bio on Monday said its T cell therapy, when used in people with certain blood cancers, reduced the risk of treatment complications seen with bone marrow transplants. The company now ...

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Incyte's stock sinks as povorcitinib disappoints in hidradenitis suppurativa

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All selected drugmakers agree to round 2 of price negotiations

The second round of Medicare price negotiations is now underway for all 15 selected drugs with signed agreements in place from the manufacturers of those drugs. Twelve manufacturers will negotiate the...

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AstraZeneca reports Phase 3 win for hypoparathyroidism drug eneboparatide

AstraZeneca’s $1.05 billion bet on French biotech Amolyt Pharma seems to be paying off. On Monday, the UK drugmaker reported a late-stage success for the hypoparathyroidism drug that sparked the...

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WuXi AppTec's US revenue growth continues to dip in post-Biosecure environment

A year after the Biosecure Act was introduced, WuXi AppTec’s US revenue growth continued to drop significantly, and the Chinese manufacturer failed to grow its customer base for the first time in five...

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AstraZeneca inks deal with Alteogen for subcutaneous cancer drugs

AstraZeneca is betting roughly $1.35 billion on Korean biotech Alteogen to help develop under-the-skin versions of multiple oncology therapies. The British pharma will license ALT-B4, a compound that...

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Trump’s HHS defends Biden-era stance on 340B rebate models

The Trump administration defended HHS’ rejection of drugmakers' 340B rebate models “at this time,” but suggested that the agency could be open to further consideration. The comments, made in response...

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FDA staff return to White Oak campus after Trump administration push

Packed parking, long security lines and traffic greeted returning FDA workers on Monday, who were called back to the agency's main White Oak campus as part of the Trump administration's effort to force...

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Sofinnova raises €165M for new early-stage biotech fund

European life sciences investor Sofinnova Partners disclosed a €165 million acceleration fund on Tuesday to back early-stage science in Italy, France, the United Kingdom and Denmark. The fund,...

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CRISPR startup Arbor Biotechnologies raises $73.9M as it nears first trial

Arbor Biotechnologies, a startup founded by CRISPR pioneer Feng Zhang nine years ago, has closed a $73.9 million Series C financing to bring its first therapy into clinical trials — a treatment that...

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Novartis revamps commercial strategy as Entresto patent cliff looms 

With its decadelong US patent for Entresto set to expire in a few months, Novartis has started to overhaul its commercial approach. The drugmaker is laying off hundreds of employees and will instead...

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Japan's RegCell raises $45.8M for Treg cell therapies, will move to US

Cell therapy biotech RegCell is hoping to bridge science from Japan with the US biotech industry to develop new cell therapies for autoimmune conditions. It announced Tuesday that it raised $45.8...

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Foodsmart names former Amwell executive Kurt Knight as CEO

Nutrition telehealth company Foodsmart tapped Kurt Knight, a former Amwell executive, to be its new CEO. The San Francisco-based company matches users with virtual dietitians and provides personalized...

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Sixteen-year-old dies after receiving Sarepta’s Duchenne therapy Elevidys

A teenage boy who received Sarepta’s Duchenne muscular dystrophy gene therapy Elevidys died from liver failure, the biotech said Tuesday morning. Sarepta told Endpoints News he was 16 years old and was...

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Stoke CEO Ed Kaye to depart shortly after inking Biogen pact and before its...

In a surprise move, the longtime CEO of Stoke Therapeutics is leaving the company, weeks before the Phase 3 trial of its lead drug is slated to start. The biotech

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